Following on from their breakthrough human trial that successfully reprogrammed the immune system to overpower glioblastoma, an aggressive brain tumor, the same scientists have now further developed the mRNA vaccine to fight not one but any cancer. It has the potential to do away with chemotherapy,…
  • iturnedintoanewt@lemmy.worldEnglish
    0·
    1 hour ago

    Previous research has focused more on homing in on a target or tailoring a vaccine specific to a patient’s own cancer profile.

    “This study suggests a third emerging paradigm,” said study co-author Duane Mitchell, MD. “What we found is by using a vaccine designed not to target cancer specifically but rather to stimulate a strong immunologic response, we could elicit a very strong anticancer reaction. And so this has significant potential to be broadly used across cancer patients – even possibly leading us to an off-the-shelf cancer vaccine.”

    So… Kinda triggering your own auto-inmune response. But I’d be wary of trouble with overtly aggressive auto-inmune responses, as we already have quite a few diseases coming from these, as well.

  • SabinStargem@lemmy.todayEnglish
    0·
    9 hours ago

    Hopefully, the researchers will be fully employed by the EU. I wouldn’t trust the US to not fuck up this miracle.

  • betterdeadthanreddit@lemmy.worldEnglish
    0·
    10 hours ago

    Curing (or at least improving our treatments for) cancer would be great. There’s a small part of me that absolutely does not want to see it happen within the next few years because of the current administration. It’d still be an overwhelmingly good thing to accomplish but I dread the future arguments over the time Dr. Don and Bobby got together in the lab to cure cancer through the power of Jesus, bootstraps and grit.

  • Komodo Rodeo@lemmy.worldEnglish
    0·
    10 hours ago

    Sweet baby Jesus, is this it? Is this finally the cure for cancer that everyone’s been waiting for?

    • wabafee@lemmy.worldEnglish
      0·
      7 hours ago

      My bet this one does cure cancer but makes your immune system too reactive in turn behave like how COVID kills people.

  • half coffee@lemy.lolEnglish
    0·
    11 hours ago

    I was recently in a conference about synthetic biological approaches to deal with cancer. The only quote I wrote down was “this approach kills cancer in a petri dish, but so does a shotgun”

  • JohnnyFlapHoleSeed@lemmy.worldEnglish
    0·
    11 hours ago

    Sounds great, but don’t get excited, it’s not for you. It will be priced so that poorz can’t afford it, like 5-15 mil a pop

  • Grandwolf319@sh.itjust.worksEnglish
    0·
    11 hours ago

    While the formulation isn’t unlike the Covid-19 vaccine, which uses lipid nanoparticles to deliver the genetic instructions to the body, it is still somewhat different. Instead of the drug encoding a virus protein, it sends a message to the immune system to rally the troops. It essentially tells the body to produce certain proteins that stimulate the immune system – including a protein within cancer cells known as PD-L1 (Programmed Death-Ligand 1), which makes tumors become more visible to immune cells.

    TLDR: they are finding it more effective by making cancer more visible and having the body’s immune system do its thing.