If you want a bit of a deeper dive, Sean Carroll’s Mindscape gets into the science of aging and known workable remedies/treatments.
The good news is that Billionaires will not be living forever any time soon.
The bad news is that we’ve got a cellularly defined terminal limit and there’s nothing we can do to simply reset the clock. “Cloned Bodies” for animals are dysfunctional bordering on nightmarish. The human brain’s plasticity isn’t something you can renew with a pill or a potion. Blood Boys don’t work. There aren’t trivially replaceable components in the human body.
Its wild this research is even being attempted, its borderline unethical to experiment on otherwise healthy people.
I fully don’t expect immune system driven aging to be understood until the Thymus better understood. DNA reproduction and telomere related aging will not be addressable until cell to cell signaling is finally mapped, and methylation activation/deactivation can be targeted.
Most likely some kind of cloned brain tissue can help reduce age-related cognitive decline and some diseases. Imo we’d get far more out of targeting specific diseases than going after aging.
I’d be fine with billionaires getting it first. As much as I’m not a fan of late stage capitalism, I refuse to cut off my nose to spite my face; they got A/C, feather beds, cars, baths, and all sorts of other luxuries long before us plebs got them. Let them beta test the stuff, and by the time the economies of scale pick up enough for it to be affordable to the rest of us, the kinks will be worked out.
Of course there’s always the possibility of a cartel withholding it from the masses, but that’s what the second amendment and guillotines were invented for.
It’s possible in the sense that you can get near identical genetic replicas of the parent organism.
But the side effect of this process is in line with historical experiments of inbreeding. Most notably, you get a high instance of progeria, which is the opposite of what you want when aiming for life extension.
You are acting as if it is an unsolvable problem.
It is an unsolved problem. Whether it is solveable (either theoretically or practically) is an unanswered question.
But there’s a real possibility that “anti-aging” is, at its heart, a war against entropy that we can’t win.
The best we can do may be to archive the information of a subject and pass it on to an inheritor. And we’ve already got a good handle on that, by way of schools and libraries.
Or maybe not. Maybe there’s a trick to indefinite cellular repair and replacement. It’s just not anywhere on the horizon. If it exists, the closest we’ve come so far is hypothesis. Nothing we’ve tried has successfully undone aging, even at a single cell level.
But there’s a real possibility that “anti-aging” is, at its heart, a war against entropy that we can’t win.
You’re going to need to provide some citation on that one because I see no evidence that this is a fundamentally unsolvable problem. It’s not a mathematics issue, it’s a scientific one. As far as I can tell there’s no biological reason that organisms need to age and die, (see lobsters) so it isn’t a war against entropy because entropy isn’t biological aging. They have nothing to do with each other.
All of the above you would know if you weren’t intent on being a disingenuous twit.
You’re going to need to provide some citation on that one
I linked to the podcast which has citations to the research in the show notes.
All of the above you would know if you weren’t intent on being a disingenuous twit.
Take it up with the Second Law of Thermodynamics and Decay Theory of Immediate Memory. You’re trying to turn a human into a Ship of Theseus, but at best all you’re doing is imperfectly copying and replicating the information therein. We run into the same problems with computer memory, and the only real working solution is to make multiple perfect copies at discrete intervals as backup.
That’s simply not possible at the cellular level at this time. Nor would backup/restore of cellular data be a practical solution, particularly as it regards the human brain, any time in the foreseeable future.
You’re doomed to die, just like everything else that’s existed to date.
That’s not how the laws of the thermodynamics works. Biological immortality is perfectly possible and we see it all the time in nature please look it up.
Cellular decay is a consequence of entropy. The solution to decay is replication. But replication is imperfect because of errors in the process. You’re still dealing with decay, only this time it is in information.
If you want a bit of a deeper dive, Sean Carroll’s Mindscape gets into the science of aging and known workable remedies/treatments.
The good news is that Billionaires will not be living forever any time soon.
The bad news is that we’ve got a cellularly defined terminal limit and there’s nothing we can do to simply reset the clock. “Cloned Bodies” for animals are dysfunctional bordering on nightmarish. The human brain’s plasticity isn’t something you can renew with a pill or a potion. Blood Boys don’t work. There aren’t trivially replaceable components in the human body.
Its wild this research is even being attempted, its borderline unethical to experiment on otherwise healthy people.
I fully don’t expect immune system driven aging to be understood until the Thymus better understood. DNA reproduction and telomere related aging will not be addressable until cell to cell signaling is finally mapped, and methylation activation/deactivation can be targeted.
Most likely some kind of cloned brain tissue can help reduce age-related cognitive decline and some diseases. Imo we’d get far more out of targeting specific diseases than going after aging.
I’d be fine with billionaires getting it first. As much as I’m not a fan of late stage capitalism, I refuse to cut off my nose to spite my face; they got A/C, feather beds, cars, baths, and all sorts of other luxuries long before us plebs got them. Let them beta test the stuff, and by the time the economies of scale pick up enough for it to be affordable to the rest of us, the kinks will be worked out.
Of course there’s always the possibility of a cartel withholding it from the masses, but that’s what the second amendment and guillotines were invented for.
That’s nothing to do with the back that clone is impossible and just that cloning is hard. You are acting as if it is an unsolvable problem.
It’s possible in the sense that you can get near identical genetic replicas of the parent organism.
But the side effect of this process is in line with historical experiments of inbreeding. Most notably, you get a high instance of progeria, which is the opposite of what you want when aiming for life extension.
It is an unsolved problem. Whether it is solveable (either theoretically or practically) is an unanswered question.
But there’s a real possibility that “anti-aging” is, at its heart, a war against entropy that we can’t win.
The best we can do may be to archive the information of a subject and pass it on to an inheritor. And we’ve already got a good handle on that, by way of schools and libraries.
Or maybe not. Maybe there’s a trick to indefinite cellular repair and replacement. It’s just not anywhere on the horizon. If it exists, the closest we’ve come so far is hypothesis. Nothing we’ve tried has successfully undone aging, even at a single cell level.
You’re going to need to provide some citation on that one because I see no evidence that this is a fundamentally unsolvable problem. It’s not a mathematics issue, it’s a scientific one. As far as I can tell there’s no biological reason that organisms need to age and die, (see lobsters) so it isn’t a war against entropy because entropy isn’t biological aging. They have nothing to do with each other.
All of the above you would know if you weren’t intent on being a disingenuous twit.
I linked to the podcast which has citations to the research in the show notes.
Take it up with the Second Law of Thermodynamics and Decay Theory of Immediate Memory. You’re trying to turn a human into a Ship of Theseus, but at best all you’re doing is imperfectly copying and replicating the information therein. We run into the same problems with computer memory, and the only real working solution is to make multiple perfect copies at discrete intervals as backup.
That’s simply not possible at the cellular level at this time. Nor would backup/restore of cellular data be a practical solution, particularly as it regards the human brain, any time in the foreseeable future.
You’re doomed to die, just like everything else that’s existed to date.
That’s not how the laws of the thermodynamics works. Biological immortality is perfectly possible and we see it all the time in nature please look it up.
Cellular decay is a consequence of entropy. The solution to decay is replication. But replication is imperfect because of errors in the process. You’re still dealing with decay, only this time it is in information.
Point to the immortal organism.