A bit subtle, especially if you weren’t familiar with medicines at the time, but the blue pill is supposed to represent an antidepressant (Prozac was apparently blue at that time, don’t know about now, and was commonly prescribed to closeted trans women instead of actually addressing the core issue), and the red pill HRT (one of the common hormone pills at the time was red)

Which makes the “redpill” movement extra hilarious.

As said, though, it was really subtle if you knew that and completely opaque if you didn’t