AI answer:

Yes, a decline in weight, even in otherwise healthy older adults, can be an early, non-cognitive sign of increased risk for dementia and Alzheimer’s disease. Studies have found that weight loss can precede symptoms of cognitive impairment and may indicate underlying Alzheimer’s biomarkers in the brain, such as the accumulation of Tau and Beta-amyloid proteins. If you, or a loved one, experience unintentional weight loss, it’s crucial to speak with a healthcare provider to investigate the cause and discuss potential next steps, as weight loss is a significant indicator of potential health issues.

Why weight loss is a concern Early indicator: Weight loss can be a subtle signal of developing dementia, sometimes appearing up to 20 years before cognitive symptoms become apparent. Biomarker connection: The weight loss may be linked to the accumulation of proteins in the brain (Beta-amyloid and Tau) that are known to be associated with Alzheimer’s disease. Potential underlying issues: Weight loss can also result from other conditions or medications that may be contributing to cognitive decline. What to do if you notice unintentional weight loss Consult a doctor: Speak with a healthcare provider to discuss the weight loss, especially if it’s unintentional or happens without a clear diet or lifestyle change. Investigate causes: A healthcare provider can help determine if there’s an underlying medical condition, a medication side effect, or a decrease in appetite that needs to be addressed. Focus on a healthy lifestyle: For those without dementia, adopting a healthy diet, engaging in regular physical activity, and prioritizing sleep can support overall brain health and potentially reduce dementia risk.

It’s a mimic!