On version 0.19 you can block instances so that you don’t see any posts from that instance, instead of having to block communities one by one, you still see comments from users of that instance in other posts so it isn’t completely blocking the instance.
hexbear
If only it blocked the users too.
It blocks their replies from reaching your inbox but I really wish it blocked their comments generally too or at least put them behind a content warning/hides it.