I never thought about it before but I use upstream and downstream without much though. For my personal devices and containers I use Fedora but when it comes to servers and VMs I use Debian for its stable nature.
I also run Linux mint in my homelab with pcie pass though so it functions like a normal desktop.
I usually was switching to different distro, when I kill my current one. Stuck with Silverblue for almost a year allready 😶