EDIT: Let’s cool it with the downvotes, dudes. We’re not out to cut funding to your black hole detection chamber or revoke the degrees of chiropractors just because a couple of us don’t believe in it, okay? Chill out, participate with the prompt and continue with having a nice day. I’m sure almost everybody has something to add.
There’s different definitions of depression, for one.
And “do a better job” is going to be defined by the individual.
But there are SSRIs, SNRIs and SDRIs like Wellbutrin. They have vastly different side effects and play on different systems (serotonin, norepinephrine and dopamine) many people find SNRIs to be more effective, but again it’s all the individual.